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Chronic Pulmonary Obstructive Disorder (COPD): Update Bulletin #3 [January 2019]

Product Code:
Publication Date:
January 2019

This edition presents the views and insights from three key opinion leaders (KOLs) from North America and Europe on a variety of recent events in the COPD market. Within this update, KOLs provided their views on the following key events: GlaxoSmithKline and Innoviva announcing that the EC has authorised an expanded label for once-daily Trelegy Ellipta; the EMA’s CHMP adopting a positive opinion recommending a label change for Chiesi’s Trimbow, already approved for the treatment of COPD; and AstraZeneca announcing that the EC has approved Bevespi Aerosphere in a pressurised metered-dose inhaler as a maintenance treatment for COPD.

Business Questions:

• How do KOLs view the IMPACT study data for Trelegy Ellipta in COPD?
• What impact do KOLs expect from the label extension for Trelegy Ellipta and how will it influence physician prescribing behaviour?
• Do experts have any cost concerns with Trelegy Ellipta?
• How do KOLs see Chiesi’s Trimbow in relation to GSK’s Trelegy Ellipta?
• Which factors influence physician prescribing behaviour for fixed triple combinations?
• Will Trimbow’s label expansion help it to compete more effectively in the market?
• On what basis are physicians selecting patients to be prescribed the triple therapy?
• How do experts view the pMDI inhaler device for Bevespi Aerosphere?
• How do KOLs view the uptake of Bevespi Aerosphere in the main markets?
• To compete effectively what do KOLs suggest AstraZeneca will need to do in this segment and why?


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