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Breast Cancer: Update Bulletin #2 [November 2018]

Product Code:
Publication Date:
November 2018

Gain new KOL insights on the latest events that have the potential to impact the treatment landscape of breast cancer (BC). Topics covered include expert opinions on: the FDA’s approval of Pfizer's Talzenna (talazoparib), a PARP inhibitor for use in patients with germline BRCA-mutated, HER2-negative locally advanced or metastatic BC; Novartis  announcing positive results from the global Phase III SOLAR-1 trial evaluating the alpha-specific PI3K inhibitor alpelisib in combination with fulvestrant; as well as SELLAS Life Sciences Group announcing data from a Phase IIb trial of the combination of NeuVax  +/- Herceptin targeting HER2 low-expressing BC patient cohorts.

Business Questions:

• How do KOLs view the FDA approval of Talzenna (talazoparib)?
• According to KOLs, how will Talzenna be positioned?
• According to KOLs, what factors will be important in determining how successful Talzenna will be against Lynparza (olaparib)?
• What is the KOLs’ reaction to the alpelisib Phase III SOLAR-1 data?
• How does Novartis’ alpelisib compare to Roche’s taselisib?
• If approved, how do KOLs think alpelisib will be positioned?
• What do KOLs think of NeuVax Phase IIb data in HER2 low-expressing TNBC patients?


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